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Clinical

Stimulation by LPS and HMGB1 in peripheral blood neutrophils from patients with sepsis-induced acute lung injury-GSE3037

Purpose

Peripheral blood neutrophils were isolated from septic patients and treated in vitro with LPS or HMGB1

Hypothesis

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Experimental Design

8 patients, each contributing a control, LPS-treated, and HMGB1-treated neutrophil sample.

Experimental Variables

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Controls

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Methods

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Additional Information

Silva E, Arcaroli J, He Q, Svetkauskaite D et al. HMGB1 and LPS induce distinct patterns of gene expression and activation in neutrophils from patients with sepsis-induced acute lung injury. Intensive Care Med 2007 Oct;33(10):1829-39. PMID: 17581740

Microarray
Affymetrix HG-U133A
24 Samples Loaded: 24
Human (Homo sapiens)
Neutrophils
Sepsis
Sample Set Spreadsheet
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Samples Preview
Sample ID !Sample_title none provided Culture conditions
GSM66867 Patient 05 control True Control
GSM66868 Patient 06 control True Control
GSM66869 Patient 07 control True Control
GSM66870 Patient 08 control True Control
GSM66871 Patient 09 control True Control
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File
sampleset4000044_sampleannotations.csv
Sample Set Spreadsheet
Raw Signal
Raw Signal
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Clinical Datasource
Links

Samples Viewer / Editor

All fields are editable except the "Sample ID" column. To edit a cell, click within the cell. To edit a "date" cell, click on the calendar icon. To cancel an edit, press the ESC key.

Sample ID !Sample Title None provided Culture conditions
GSM66867
Patient 05 control
True
Control
GSM66868
Patient 06 control
True
Control
GSM66869
Patient 07 control
True
Control
GSM66870
Patient 08 control
True
Control
GSM66871
Patient 09 control
True
Control
GSM66872
Patient 12 control
True
Control
GSM66873
Patient 15 control
True
Control
GSM66874
Patient 19 control
True
Control
GSM66875
Patient 05 HMGB1 treated
True
HMGB1
GSM66876
Patient 06 HMGB1 treated
True
HMGB1
GSM66877
Patient 07 HMGB1 treated
True
HMGB1
GSM66878
Patient 08 HMGB1 treated
True
HMGB1
GSM66879
Patient 09 HMGB1 treated
True
HMGB1
GSM66880
Patient 12 HMGB1 treated
True
HMGB1
GSM66881
Patient 15 HMGB1 treated
True
HMGB1
GSM66882
Patient 19 HMGB1 treated
True
HMGB1
GSM66883
Patient 05 LPS treated
True
LPS
GSM66884
Patient 06 LPS treated
True
LPS
GSM66885
Patient 07 LPS treated
True
LPS
GSM66886
Patient 08 LPS treated
True
LPS
GSM66887
Patient 09 LPS treated
True
LPS
GSM66888
Patient 12 LPS treated
True
LPS
GSM66889
Patient 15 LPS treated
True
LPS
GSM66890
Patient 19 LPS treated
True
LPS

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