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SIDRA

GXB

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Description

Expression changes induced by transmigration in human neutrophils-GSE2322

Purpose

Human volunteers were exposed to endotoxin by bronchoscopic instillation, airspace and circulating neutrophils were isolated 16 hours later and compared to circulating neutrophils obtained prior to endotoxin exposure, and to circulating neutrophils exposed to endotoxin in vitro.

Experimental Design

Human volunteers were exposed to endotoxin by bronchoscopic instillation, airspace and circulating neutrophils were isolated 16 hours later and compared to circulating neutrophils obtained prior to endotoxin exposure, and to circulating neutrophils exposed to endotoxin in vitro.

Additional Information
  • Coldren CD, Nick JA, Poch KR, Woolum MD et al. Functional and genomic changes induced by alveolar transmigration in human neutrophils. Am J Physiol Lung Cell Mol Physiol 2006 Dec;291(6):L1267-76. PMID: 16861384
  • Platform Affymetrix HG-U133A
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